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IRIS (biosensor)
Interferometric Reflectance Imaging Sensor (IRIS), formerly known as the Spectral Reflectance Imaging Biosensor (SRIB),〔 〕 is a system that can be used as a biosensing platform capable of high-throughput multiplexing of protein-protein, protein-DNA, and DNA-DNA interactions without the use of any fluorescent labels. The sensing surface is prepared by robotic spotting of biological probes that are immobilized on functionalized Si/SiO2 substrates. IRIS is capable of quantifying bimolecular mass accumulated on the surface.
==Measurement==
To perform a measurement, the sample is illuminated with multiple different wavelengths from either a tunable laser or different color LEDs; typically speaking, a relatively narrow bandwidth optical source. The reflection intensity is imaged using a CCD or CMOS camera. By using interferometric techniques, nanometer changes can be detected.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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